Dermoscopy of Lentiginous Melanomas and Equivocal Benign Pigmented Macules of the Scalp: A Case-Control Multicentric Study

医学 皮肤病科 头皮 恶性雀斑黑色素瘤 恶性痣 页面ID 前额 雀斑 结节性黑色素瘤 恶性肿瘤 病理 黑色素瘤 外科 免疫组织化学 癌症研究
作者
Amanda Pereira,Sérgio Henrique Hirata,Paweł Pietkiewicz,Scott W. Menzies,Gabriella Brancaccio,Helena Collgros,Giuseppe Argenziano,Serigne Lo,Tasnia Ahmed,Riccardo Pampena,Caterina Longo,Pascale Guitera
出处
期刊:Dermatology [Karger Publishers]
卷期号:240 (1): 132-141
标识
DOI:10.1159/000535030
摘要

Although the dermoscopic features of facial lentiginous melanomas (LM), including lentigo maligna and lentigo maligna melanoma, have been extensively studied, the literature about those located on the scalp is scarce. This study aims to describe the dermoscopic features of scalp LM and assess the diagnostic accuracy of dermoscopy to discriminate them from equivocal benign pigmented macules.Consecutive cases of scalp LM and histopathology-proven benign but clinically equivocal pigmented macules (actinic keratoses, solar lentigos, seborrhoeic keratoses, and lichen planus-like keratoses) from four referral centres were included. Dermoscopic features were analysed by two blinded experts. The diagnostic performance of a predictive model was assessed.56 LM and 44 controls were included. Multiple features previously described for facial and extrafacial LM were frequently identified in both groups. Expert's sensitivity to diagnose scalp LM was 76.8% (63.6-87.0) and 78.6% (65.6-88.4), with specificity of 54.5% (38.9-69.6) and 56.8% (41.0-71.7), and fair agreement (kappa coefficient 0.248). The strongest independent predictors of malignancy were (OR, 95% CI) chaos of colour (15.43, 1.48-160.3), pigmented reticular lines (14.96, 1.68-132.9), increased density of vascular network (3.45, 1.09-10.92), and perifollicular grey circles (2.89, 0.96-8.67). The predictive model achieved 85.7% (73.8-93.6) sensitivity, 61.4% (45.5-75.6) specificity, and 81.5 (73.0-90.0) area under curve to discriminate benign and malignant lesions. A diagnostic flowchart was proposed, which should improve the diagnostic performance of dermoscopy.Both facial and extrafacial dermoscopic patterns can be identified in scalp LM, with considerable overlap with benign pigmented macules, leading to low specificity and interobserver agreement on dermoscopy.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
mufcyang完成签到,获得积分10
1秒前
了晨完成签到 ,获得积分10
2秒前
yi完成签到 ,获得积分10
5秒前
wxnice完成签到,获得积分10
6秒前
量子星尘发布了新的文献求助10
8秒前
星辰大海应助大橙子采纳,获得10
17秒前
17秒前
七QI完成签到 ,获得积分10
18秒前
21秒前
褚香旋完成签到,获得积分10
21秒前
一只狗东西完成签到 ,获得积分10
23秒前
宇老师发布了新的文献求助10
24秒前
25秒前
qiqi发布了新的文献求助30
27秒前
大橙子发布了新的文献求助10
30秒前
wzhang完成签到,获得积分10
31秒前
ken131完成签到 ,获得积分10
34秒前
myl完成签到,获得积分10
35秒前
728完成签到,获得积分10
41秒前
xiaofeng5838完成签到,获得积分10
41秒前
ronnie完成签到,获得积分10
41秒前
44秒前
寒冷芷蕊完成签到,获得积分20
44秒前
44秒前
Jane完成签到,获得积分10
44秒前
一氧化二氢完成签到,获得积分10
50秒前
凡事发生必有利于我完成签到,获得积分10
51秒前
yihaiqin完成签到 ,获得积分10
55秒前
轩辕剑身完成签到,获得积分0
55秒前
coolkid完成签到 ,获得积分0
56秒前
你怎么那么美完成签到,获得积分10
56秒前
游艺完成签到 ,获得积分10
59秒前
冬月完成签到 ,获得积分10
59秒前
薛乎虚完成签到 ,获得积分10
1分钟前
1分钟前
大胖完成签到,获得积分10
1分钟前
野火197完成签到,获得积分10
1分钟前
1分钟前
量子星尘发布了新的文献求助10
1分钟前
April完成签到,获得积分10
1分钟前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038157
求助须知:如何正确求助?哪些是违规求助? 3575869
关于积分的说明 11373842
捐赠科研通 3305650
什么是DOI,文献DOI怎么找? 1819255
邀请新用户注册赠送积分活动 892655
科研通“疑难数据库(出版商)”最低求助积分说明 815022