[Advance in epithelial-mesenchymal transition in chronic rhinosinusitis].

Chronic rhinosinusitis is a common disease in otorhinolaryngology, which has chronic inflammation in mucosa of nasal cavity and sinus. The mechanisms of chronic rhinosinusitis is still unknown. Recently, some studies show that tissue remodeling has important roles in chronic rhinosinusitis, and as a part of tissue remodeling, epithelial-mesenchymal transition also received high attention. Therefore, this review will summarize the present studies involve epithelial-mesenchymal transition and chronic rhinosinusitis, so as to provide reference for further exploring the pathogenesis of chronic sinusitis.慢性鼻窦炎是一种常见的耳鼻咽喉科疾病，表现为鼻及鼻窦黏膜组织的慢性炎症，其发病机制的研究尚不全面。目前有研究认为组织重塑在慢性鼻窦炎的发病中起到了重要的作用，而上皮-间质转化作为组织重塑中重要的一环也受到了高度关注。因此，本文将对上皮-间质转化与慢性鼻窦炎之间的研究进行综述，为进一步探究慢性鼻窦炎的发病机制提供参考。.