表观遗传学
生物
基因组学
计算生物学
基因组
功能基因组学
遗传学
基因
DNA甲基化
基因表达
作者
Cheng Luo,Alisdair R. Fernie,Jianbing Yan
标识
DOI:10.1016/j.tplants.2020.04.016
摘要
The development of genomics and epigenomics has allowed rapid advances in our understanding of plant biology. However, conventional bulk analysis dilutes cell-specific information by providing only average information, thereby limiting the resolution of genomic and functional genomic studies. Recent advances in single-cell sequencing technology concerning genomics and epigenomics open new avenues to dissect cell heterogeneity in multiple biological processes. Recent applications of these approaches to plants have provided exciting insights into diverse biological questions. We highlight the methodologies underlying the current techniques of single-cell genomics and epigenomics before covering their recent applications, potential significance, and future perspectives in plant biology.
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