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Journal of Medical VirologyVolume 41, Issue S1 p. 2-6 Article Acyclovir: Discovery, mechanism of action, and selectivity Dr. G. B. Elion, Corresponding Author Dr. G. B. Elion Wellcome Research Laboratories, Research Triangle Park, North CarolinaScientist Emeritus, Wellcome Research Laboratories, 3030 Cornwallis Road, Research Triangle Park, NC 27709===Search for more papers by this author Dr. G. B. Elion, Corresponding Author Dr. G. B. Elion Wellcome Research Laboratories, Research Triangle Park, North CarolinaScientist Emeritus, Wellcome Research Laboratories, 3030 Cornwallis Road, Research Triangle Park, NC 27709===Search for more papers by this author First published: 1993 https://doi.org/10.1002/jmv.1890410503Citations: 158AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References Biron KK, Elion GB (1980): In vitro susceptibility of varicella-zoster virus to acyclovir. Antimicrobial Agents & Chemotherapy 18: 443–447. 10.1128/AAC.18.3.443 CASPubMedWeb of Science®Google Scholar Colby BM, Furman PA, Shaw JE, Elion GB, Pagano JS (1981): Phosphorylation of acyclovir [9-(2-hydroxyethoxymethyl)guanine] in Epstein-Barr virus-infected lymphoblastoid cell lines. Journal of Virology 38: 606–611. CASPubMedWeb of Science®Google Scholar Datta AK, Colby BM, Shaw JE, Pagano JS (1980): Acyclovir inhibition of Epstein-Barr virus replication. Proceedings of the National Academy of Sciences, USA 77: 5173–5176. 10.1073/pnas.77.9.5163 Web of Science®Google Scholar Elion GB (1982): Mechanisms of action and selecticity of acyclovir. American Journal of Medicine 73(1A): 7–13. 10.1016/0002-9343(82)90055-9 CASPubMedWeb of Science®Google Scholar Elion GB (1986): History, mechanism of action, spectrum and selectivity of nucleoside analogs. In J Mills, L Corey (eds): “ New Directions for Clinical Application and Research.” New York: Elsevier, pp 118–137. 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CASPubMedWeb of Science®Google Scholar Schaeffer HJ, Beauchamp L, DeMiranda P, Elion GB, Bauer DJ, Collins P (1978): 9-(2-Hydroxyethoxymethyl)guanine activity against viruses of the herpes group. Nature 272: 583–585. 10.1038/272583a0 CASPubMedWeb of Science®Google Scholar St Clair MH, Furman PA, Lubbers CM, Elion GB (1980): Inhibition of cellular α and virally induced deoxyribonucleic acid polymerases by the triphosphate of acyclovir. Antimicrobial Agents & Chemotherapy 18: 742–745. 10.1128/AAC.18.5.741 Google Scholar Citing Literature Volume41, IssueS1Supplement: Proceeding from an international symposium held in Berlin, Germany1993Pages 2-6 ReferencesRelatedInformation