双苄基
DPPH
石斛
化学
立体化学
菲
清除
有机化学
抗氧化剂
植物
生物
作者
Dan Yang,Liang-Yan Liu,Zhong‐Quan Cheng,Feng-Qing Xu,Weiwei Fan,Cheng‐Ting Zi,Fa-Wu Dong,Jun Zhou,Zhong‐Tao Ding,Jiang‐Miao Hu
出处
期刊:Fitoterapia
[Elsevier]
日期:2014-11-11
卷期号:100: 11-18
被引量:50
标识
DOI:10.1016/j.fitote.2014.11.004
摘要
One new phenanthrene, aphyllone A (1) and four new bibenzyl derivatives, aphyllone B (2) and aphyllals C-D (3-5), together with nine known compounds (6-14), were isolated from the stems of Dendrobium aphyllum (Roxb.) C. E. Fischer. The structures of these new compounds were elucidated by means of extensive spectroscopic analyses, and the absolute configuration of compound 1 was determined by single crystal X-ray diffraction and quantum calculations. Compounds 6, 8 and 14 inhibited NO production at the concentration of 25 μM in LPS-stimulated RAW264.7 cells with the inhibition (%) of 32.48, 35.68, and 38.50. Compound 2 possessed significant DPPH radical scavenging activity with scavenging percentage of 87.97% at the concentration of 100 μg/mL.
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