医学
牙骨质
根管
牙髓(牙)
血运重建
牙科
牙本质
结缔组织
冠状面
人类牙齿
前磨牙
解剖
臼齿
病理
心肌梗塞
搪瓷漆
精神科
作者
Patricia Becerra,Domenico Ricucci,Simona Loghin,Jennifer L. Gibbs,Louis M. Lin
标识
DOI:10.1016/j.joen.2013.07.017
摘要
IntroductionHistologic studies of teeth from animal models of revascularization/revitalization are available; however, specimens from human studies are lacking. The nature of tissues formed in the canal of human revascularized/revitalized teeth was not well established.MethodsAn immature mandibular premolar with infected necrotic pulp and a chronic apical abscess was treated with revascularization/revitalization procedures. At both the 18-month and 2-year follow-up visits, radiographic examination showed complete resolution of the periapical lesion, narrowing of the root apex without root lengthening, and minimal thickening of the canal walls. The revascularized/revitalized tooth was removed because of orthodontic treatment and processed for histologic examination.ResultsThe large canal space of revascularized/revitalized tooth was not empty and filled with fibrous connective tissue. The apical closure was caused by cementum deposition without dentin. Some cementum-like tissue was formed on the canal dentin walls. Inflammatory cells were observed in the coronal and middle third of revascularized/revitalized tissue.ConclusionsIn the present case, the tissue formed in the canal of a human revascularized/revitalized tooth was soft connective tissue similar to that in the periodontal ligament and cementum-like or bone-like hard tissue, which is comparable with the histology observed in the canals of teeth from animal models of revascularization/revitalization.
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