封锁
贫血
医学
疾病
癌症研究
红细胞
血细胞
免疫学
药理学
内科学
受体
出处
期刊：Cancer Discovery
[American Association for Cancer Research]
日期：2020-06-01
卷期号：10 (6): OF6-OF6
标识
DOI：10.1158/2159-8290.cd-nb2020-035
摘要
Abstract IL6 blockade helped promote the differentiation of red blood cell precursors, leading to reduced anemia and prolonged survival in a xenograft mouse model of AML. If validated in patients, the therapeutic strategy could reduce the need for blood transfusions, but it would not target the root cause of the disease.
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