Exercise‐induced α‐ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1‐dependent adrenal activation

Corrigendum15 July 2021free access Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation Yexian Yuan Yexian Yuan Search for more papers by this author Pingwen Xu Pingwen Xu Search for more papers by this author Qingyan Jiang Qingyan Jiang Search for more papers by this author Xingcai Cai Xingcai Cai Search for more papers by this author Tao Wang Tao Wang Search for more papers by this author Wentong Peng Wentong Peng Search for more papers by this author Jiajie Sun Jiajie Sun Search for more papers by this author Canjun Zhu Canjun Zhu Search for more papers by this author Cha Zhang Cha Zhang Search for more papers by this author Dong Yue Dong Yue Search for more papers by this author Zhihui He Zhihui He Search for more papers by this author Jinping Yang Jinping Yang Search for more papers by this author Yuxian Zeng Yuxian Zeng Search for more papers by this author Man Du Man Du Search for more papers by this author Fenglin Zhang Fenglin Zhang Search for more papers by this author Lucas Ibrahimi Lucas Ibrahimi Search for more papers by this author Sarah Schaul Sarah Schaul Search for more papers by this author Yuwei Jiang Yuwei Jiang Search for more papers by this author Jiqiu Wang Jiqiu Wang Search for more papers by this author Jia Sun Jia Sun Search for more papers by this author Qiaoping Wang Qiaoping Wang Search for more papers by this author Liming Liu Liming Liu Search for more papers by this author Songbo Wang Songbo Wang Search for more papers by this author Lina Wang Lina Wang Search for more papers by this author Xiaotong Zhu Xiaotong Zhu Search for more papers by this author Ping Gao Ping Gao Search for more papers by this author Qianyun Xi Qianyun Xi Search for more papers by this author Cong Yin Cong Yin Search for more papers by this author Fan Li Fan Li Search for more papers by this author Guli Xu Guli Xu Search for more papers by this author Yongliang Zhang Yongliang Zhang Search for more papers by this author Gang Shu Corresponding Author Gang Shu [email protected] orcid.org/0000-0002-1321-4396 Search for more papers by this author Yexian Yuan Yexian Yuan Search for more papers by this author Pingwen Xu Pingwen Xu Search for more papers by this author Qingyan Jiang Qingyan Jiang Search for more papers by this author Xingcai Cai Xingcai Cai Search for more papers by this author Tao Wang Tao Wang Search for more papers by this author Wentong Peng Wentong Peng Search for more papers by this author Jiajie Sun Jiajie Sun Search for more papers by this author Canjun Zhu Canjun Zhu Search for more papers by this author Cha Zhang Cha Zhang Search for more papers by this author Dong Yue Dong Yue Search for more papers by this author Zhihui He Zhihui He Search for more papers by this author Jinping Yang Jinping Yang Search for more papers by this author Yuxian Zeng Yuxian Zeng Search for more papers by this author Man Du Man Du Search for more papers by this author Fenglin Zhang Fenglin Zhang Search for more papers by this author Lucas Ibrahimi Lucas Ibrahimi Search for more papers by this author Sarah Schaul Sarah Schaul Search for more papers by this author Yuwei Jiang Yuwei Jiang Search for more papers by this author Jiqiu Wang Jiqiu Wang Search for more papers by this author Jia Sun Jia Sun Search for more papers by this author Qiaoping Wang Qiaoping Wang Search for more papers by this author Liming Liu Liming Liu Search for more papers by this author Songbo Wang Songbo Wang Search for more papers by this author Lina Wang Lina Wang Search for more papers by this author Xiaotong Zhu Xiaotong Zhu Search for more papers by this author Ping Gao Ping Gao Search for more papers by this author Qianyun Xi Qianyun Xi Search for more papers by this author Cong Yin Cong Yin Search for more papers by this author Fan Li Fan Li Search for more papers by this author Guli Xu Guli Xu Search for more papers by this author Yongliang Zhang Yongliang Zhang Search for more papers by this author Gang Shu Corresponding Author Gang Shu [email protected] orcid.org/0000-0002-1321-4396 Search for more papers by this author Author Information Yexian Yuan, Pingwen Xu, Qingyan Jiang, Xingcai Cai, Tao Wang, Wentong Peng, Jiajie Sun, Canjun Zhu, Cha Zhang, Dong Yue, Zhihui He, Jinping Yang, Yuxian Zeng, Man Du, Fenglin Zhang, Lucas Ibrahimi, Sarah Schaul, Yuwei Jiang, Jiqiu Wang, Jia Sun, Qiaoping Wang, Liming Liu, Songbo Wang, Lina Wang, Xiaotong Zhu, Ping Gao, Qianyun Xi, Cong Yin, Fan Li, Guli Xu, Yongliang Zhang and Gang Shu * **Corresponding author. E-mail: [email protected] The EMBO Journal (2021)40:e108434https://doi.org/10.15252/embj.2021108434 This article corrects the following: Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation27 February 2020 PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info The authors approached the journal to correct a mistake in the data presented in Appendix␣Fig S3D. The authors state that the mouse images in Appendix␣Fig S3D mistakenly displayed images from Fig 2F and Appendix␣Fig S1F. The images in Appendix␣Fig S3D are herewith corrected. The authors state that this change does not affect the conclusions or the statistics. The source data for these panels have been added to the original publication. The authors note that the following sentence needs to be corrected from: Appendix Figure S3D. Original. Appendix Figure S3D. Corrected. “Interestingly, several well-established accumulation signatures of succinate, malate, hypoxanthine, and xanthine induced by endurance exercise (Lewis et␣al, 2010) were found to be decreased by endurance exercise (Figs 1D and EV1A–D)”. to “Interestingly, several well-established accumulation signatures of succinate, malate, hypoxanthine, and xanthine induced by endurance exercise (Lewis et␣al, 2010) were found to be decreased by resistance exercise (Figs 1D and EV1A–D)”. Further, the authors requested to amend the legend of Appendix␣Fig S3R to indicate that the same sample for the iWAT group, “WT+2%AKG” treatment, is shown in Fig 3P. The corrected legend reads: “(R-S). Representative images (R) and quantification (S) of p-HSL DAB staining from male OXGR1OEAG mice treated with AKG for 12 weeks (n = 6 per group). The same sample is shown as in Fig 3P”. The authors regret these errors and any confusion they may have caused. All authors approve of this correction. Next ArticlePrevious Article Read MoreAbout the coverClose modalView large imageVolume 40,Issue 14,15 July 2021This cover highlights the article Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters by G. Chi, R. Ebenhoch, H. Man, H. Tang, K.L. Dürr and colleagues. The key findings from this multidisciplinary work and additional insights from other recent studies on cation-coupled chloride transporters are discussed in the accompanying News & Views article “Transport unplugged: KCCs are regulated through an N-terminal plug of the ion pathway” by R.K. Flygaard and colleagues. The cover art illustrates cryo-electron microscopy structures of the human potassium chloride transporters KCC1 and KCC3 embedded into a lipid bilayer using MD simulations. A domain-swapped dimer of KCC1 (shown in cyan/orange) with ATP bound to its C-terminal cytoplasmic domain is displayed in front, while a fuzzy representation of phospho-mimetic, auto-inhibited KCC3 (shown in pink/navy) is visible in the background of the bilayer. (Scientific image by Ben Tehan and Norberto Escudero Urquijo) Volume 40Issue 1415 July 2021In this issue RelatedDetailsLoading ...