A biomechanical study of ligament tethers strengthening for the prevention of proximal junctional kyphosis after posterior long-segment spinal fusion

Abstract

Background

Proximal junctional kyphosis is a known complication of posterior long-segment thoracolumbar fusion. Here, the biomechanical effectiveness of ligament tethers strengthening and vertebral body augmentation, in proximal junctional kyphosis prevention was explored using the finite element analysis.

Methods

Based on a validated model of T1-L5 with the pedicle screw system instrumented T8-L5, strengthening models with different strategies were created to assess the range of motion in proximal vertebrae, vertebrae stress, pedicle screw stress, and pressure on intervertebral discs during extension, flexion, lateral bending, and axial rotation motions. Strengthening strategies included two- and three-level posterior ligament tethers (TE-T7-T9 and TE-T6-T9), and tethers with T7 &T8 vertebral body augmentation (TECE-T7-T9 and TECE-T6-T9).

Findings

Compared to the spinal fusion model, the ligament tethers strengthening significantly reduced the flexion-extension range of motion difference among the proximal vertebrae. During the flexion-extension motion, the T8 vertebra stresses in the TE-T7-T9, TE-T6-T9, TECE-T7-T9, and TECE-T6-T9 models were distinctively reduced, the values decreased by 26.8%, 28.3%, 28.8%, and 9.6%, respectively, during flexion, and by 21.9%, 35.2%, 23%, and 18.6%, respectively, during extension. In the strengthening models, the maximum stresses on the T7/T8 intervertebral disc in the TE-T6-T9 model were reduced by 13.8% during flexion and by 14.7% during extension.

Interpretation

Based on our results, the ligament strengthening configuration of the three-level posterior tethers produced a more gradual transition in range of motion, vertebrae stresses, and intervertebral discs stress between the fused and non-fused segments, especially during flexion-extension, which may significantly decrease the proximal junctional kyphosis biomechanical risk.