Full Solar‐Spectrum‐Driven Antibacterial Therapy over Hierarchical Sn3O4/PDINH with Enhanced Photocatalytic Activity

Abstract Antibacterial photocatalytic therapy (APCT) is considered to be a potential treatment for administrating antibiotic‐resistant bacteria. However, due to the low photocatalytic efficiency and weak ability to capture bacteria, it is not practically applied. In this work, an organic–metal oxide hybrid semiconductor heterostructure is fabricated for the photocatalytic generation of reactive oxygen species (ROS) to kill the drug‐resistant bacteria. The organic semiconductor, perylene diimide (PDI), can self‐assemble on Sn 3 O 4 nanosheets to form a “hook‐and‐loop” sticky surface that can capture bacteria, via large numbers of hydrogen bonding and π–π stacking interactions, which are not possible in inorganic semiconductors. This easy‐to‐fabricate hybrid semiconductor also possesses improved photocatalytic activity, which is owing to the formation of heterostructure that achieves full‐spectrum absorption, and the reduction of the photocarrier recombination rate to produce more reactive oxygen species. It has a good promoting effect on the wounds of mice infected by Staphylococcus aureus . This work shows new ideas for fabricating smart full‐spectrum inorganic–organic hybrid adhesive heterostructure photocatalysts for antibacterial photocatalytic therapy.