化学
试剂
硫
反应性(心理学)
电泳剂
废止
四氟硼酸盐
乙烯
有机化学
盐(化学)
组合化学
催化作用
离子液体
医学
病理
替代医学
作者
Fabio Juliá,Jiyao Yan,Fritz Paulus,Tobias Ritter
摘要
The use of vinyl electrophiles in synthesis has been hampered by the lack of access to a suitable reagent that is practical and of appropriate reactivity. In this work we introduce a vinyl thianthrenium salt as an effective vinylating reagent. The bench-stable, crystalline reagent can be readily prepared from ethylene gas at atmospheric pressure in one step and is broadly useful in the annulation chemistry of (hetero)cycles, N-vinylation of heterocyclic compounds, and palladium-catalyzed cross-coupling reactions. The structural features of the thianthrene core enable a distinct synthesis and reactivity profile, unprecedented for other vinyl sulfonium derivatives.
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