银纳米粒子
抗菌活性
核化学
纳米复合材料
布尼卡
大肠杆菌
粒径
枯草芽孢杆菌
纳米颗粒
最小抑制浓度
化学
傅里叶变换红外光谱
石墨烯
最低杀菌浓度
材料科学
抗菌剂
纳米技术
化学工程
细菌
有机化学
生物化学
生物
物理化学
园艺
工程类
基因
遗传学
作者
R. Ragu,R. Ragu,Joseph Sagaya Kennedy A,Jerome Das S.
摘要
Ag nanoparticles and Ag/GO nanocomposites have been synthesized by facile, eco-friendly, and cost-effective green approach using the peel extracts of Punica granatum. The synthesized Silver Nanoparticles and Silver Graphene Oxide nanocomposites were characterized by UV-visible spectroscopy, X-ray diffraction, transmission electron microscopy, and Fourier transform infrared analysis. AgNPs revealed spherical morphology with particle size ranging from 30 to 40 nm. Scanning electron microscopy results revealed silver nanoparticles with an average size of 35 nm being uniformly distributed over GO sheets. The surface plasmon band appears at 433 nm for AgNPs and 458 nm for Ag/GO nanocomposites. The green synthesized nanoparticles were found to have excellent antibacterial efficacy against both gram positive (Staphylococcus aureus, Bacillus subtilis) and gram negative (Klebsiella pneumoniae, Escherichia coli) bacterial strains. The results showed that Ag/GO nanocomposites showed better antibacterial activity than pure AgNPs with maximum inhibitory zone of 28 mm for Escherichia coli. This attributes to the role of GO sheets in preventing AgNPs from agglomerating and oxidizing. The anticancer activity of AgNPs and Ag/GO nanocomposites were tested against human breast cancer cell line (MCF-7) which demonstrated a dose dependent activity with half minimum inhibitory concentration of 100 and 150 μg/ml.
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