神经影像学
自杀意念
心理学
边缘型人格障碍
重性抑郁障碍
双相情感障碍
精神病
扣带回前部
精神科
精神分裂症(面向对象编程)
临床心理学
神经科学
毒物控制
医学
伤害预防
心情
认知
环境卫生
作者
Ali Bani‐Fatemi,Samia Tasmim,Ariel Graff‐Guerrero,Philip Gerretsen,John S. Strauss,Nathan J. Kolla,Gianfranco Spalletta,Vincenzo De Luca
标识
DOI:10.1016/j.pscychresns.2018.05.008
摘要
Brain imaging is a non-invasive and in vivo direct estimation of detailed brain structure, regional brain functioning and estimation of molecular processes in the brain. The main objective of this review was to analyze functional and structural neuroimaging studies of individuals at risk for suicide. We reviewed articles published between 2005 and 2018, indexed in PubMed and Medline, assessing structural and functional alterations of the brain of individuals at high risk for suicide and at low risk for suicide. We reviewed functional and structural neuroimaging studies which included individuals with a history of suicidal ideation or attempt in major depressive disorder (MDD), bipolar disorder (BD), psychosis, and borderline personality disorder (BPD). We selected 45 papers that focused on suicidality in MDD, 17 papers on BD, 11 papers on psychosis, and 5 papers on BPD. The suicidal brain across psychiatric diagnoses seems to heavily involve dysfunction of the fronto-temporal network, primarily involving reductions of gray and white matter volumes in the pre-frontal cortex (PFC), anterior cingulate, and superior temporal gyrus. Nonetheless, there are several ways to define suicidal behaviour and ideation. Therefore, it still remains difficult to combine the evidence from imaging studies that used different definitions of suicidality.
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