次黄嘌呤
荧光
黄嘌呤氧化酶
聚集诱导发射
细胞内
黄嘌呤
化学
生物物理学
材料科学
纳米技术
生物化学
生物
光学
物理
酶
作者
Zhiling Zhang,Ryan T. K. Kwok,Yong Yu,Ben Zhong Tang,Ka Ming Ng
摘要
Hypoxanthine is a well-known indicator of intracellular energy status that is associated with many pathological conditions. We report a fluorescent luminogen (TPE-HPro) with aggregation-induced emission (AIE) feature which, along with xanthine oxidase (XO), detects and quantifies hypoxanthine in a "turn-on" manner. The superior detection performance of this fluorometric assay indicates its great potential for biomedical diagnostics.
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