Photoredox Alkylarylation of N‐Benzyl‐N‐(2‐ethynylaryl)‐Amides with α‐Bromoalkyl Esters: Access to Dibenzazepines

Abstract A new two‐component alkylarylation of N ‐benzyl‐ N ‐(2‐ethynylaryl)amides with α ‐bromoalkyl esters using visible light photoredox catalysis promoted by silver salts for producing substituted dibenzazepines is described. Employing α ‐bromoalkyl esters to form the alkyl carbon‐centered radicals enables the alkylarylation of alkynes where two carbon‐centered functional groups are introduced across the C≡C bond in a single reaction. magnified image