前额叶腹外侧皮质
磁刺激
前额叶皮质
心理学
感知
情感知觉
扁桃形结构
功能磁共振成像
神经科学
刺激
前额叶腹内侧皮质
认知心理学
听力学
认知
医学
作者
Christina F. Chick,Cammie Rolle,Hersh Trivedi,Karen Monuszko,Amit Etkin
标识
DOI:10.1016/j.psychres.2019.112515
摘要
The lateral prefrontal cortex, a region with both structural and functional connectivity to the amygdala, has been consistently implicated in the downregulation of subcortical-generated emotional responses. Although previous work has demonstrated that the ventral lateral prefrontal cortex (vlPFC) is important to emotion processing, no study has interrupted vlPFC function in order to test is role in emotion perception. In the current study, we acutely disrupted vlPFC function in twenty healthy adult participants by administering sham stimulation and transcranial magnetic stimulation (TMS), in randomized order, during performance of an emotional perception task. During sham stimulation, participants demonstrated increased perceptual sensitivity for happy faces compared to angry faces. Disruption of the vlPFC eliminated this difference: in this condition, perceptual sensitivity did not differ between happy and angry faces. Reaction times and response bias did not differ between emotions or TMS conditions. This pattern of perceptual bias is consistent with effects observed in a wide range of affective disorders, in which vlPFC dysfunction has also been reported. This study provides insight into a possible mechanism through which the vlPFC may contribute to emotion perception.
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