Delivery of siRNA targeting HIF-1α loaded chitosan modifiedd-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) nanoparticles into nasopharyngeal carcinoma cell to improve the therapeutic efficacy of cisplatin

Nanoformulation of siRNA targeting HIF-1α loaded chitosan modified TPGS-b-(PCL-ran-PGA) NPs could increase the therapeutic potential of cisplatin for nasopharyngeal carcinoma.