Four Homoisoflavanones from Polygonatum odoratum

AIM:To study the chemical constituents from the rhizome of Polygonatum odoratum(Mill.) Druce.METHODS:The chemical constituents were isolated by chromatographic separations of silica gel and Sephadex LH-20 and their structures were elucidated on the basis of spectral analysis.RESULTS:Four homoisoflavanones were isolated and identified as(±)5,7-di-hydroxy-3-(2-hydroxy-4-methoxybenzyl)-6,8-dimethylchroman-4-one(1),(3R)-5,7-dihy-droxy-3-(4-hydroxybenzyl)-6,8-dimethylchroman-4-one(2),(3R)-5,7-dihydroxy-3-(4-hydroxybenzyl)-8-methoxy-6-methylchroman-4-one(3),and(3R)-5,7-dihydroxy-3-(4-hydroxybenzyl)-6-methyl-chroman-4-one(4).CONCLUSION:Homoisoflavanones were rare in nature.