免疫原
前药
细胞毒性T细胞
癌症研究
抗体
肺癌
人源化抗体
细胞毒性
药理学
单克隆抗体
医学
化学
肿瘤科
免疫学
体外
生物化学
出处
期刊:PubMed
日期:2005-08-01
卷期号:7 (4): 394-401
被引量:19
摘要
ImmunoGen is developing huN901-DMI, a compound comprised of a CD56-targeted humanized N901 antibody conjugated to the company's proprietary cytotoxic agent. DM1, using its tumor-activated prodrug technology, for the potential treatment of cancers that express CD56, in particular, small-cell lung cancer.
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