亚胺
立体选择性
组合化学
催化作用
蛋白质工程
化学
有机化学
酶
出处
期刊:Nature Catalysis
[Springer Nature]
日期:2019-10-11
卷期号:2 (10): 841-842
被引量:18
标识
DOI:10.1038/s41929-019-0366-8
摘要
Imine reductases are promising catalysts, facilitating a direct stereoselective route to secondary amines. Now, protein engineering has created stable and efficient variants that allow their application in kilogram-scale synthesis.
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