Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women

乳腺癌遗传关联联想（心理学）医学遗传学肿瘤科癌症生物信息学内科学生物基因基因型单核苷酸多态性心理学心理治疗师

作者

Leila Dorling,Sara Carvalho,Jamie Allen,Anna González‐Neira,Craig Luccarini,Cecilia Wahlström,Karen A. Pooley,Michael T. Parsons,Cristina Fortuño,Qin Wang,Manjeet K. Bolla,Joe Dennis,Renske Keeman,Rosario Tumino,Núria Álvarez,Belén Herráez,María Victoria Fernández,Rocío Núñez‐Torres,Ana Osório,Jeanette Valcich,Minerva Li,Therese Törngren,Patricia Harrington,Caroline Baynes,Don Conroy,Brennan Decker,Laura Fachal,Nasim Mavaddat,Thomas U. Ahearn,Conxi Lázaro,Natalia Antonenkova,Norbert Arnold,Patrick Arveux,Margreet G.E.M. Ausems,Päivi Auvinen,Heiko Becher,Matthias W. Beckmann,Sabine Behrens,Marina Bermisheva,Katarzyna Białkowska,Carl Blomqvist,Natalia Bogdanova,Nadja Bogdanova-Markov,Stig E. Bojesen,Bernardo Bonanni,Anne‐Lise Børresen‐Dale,Hiltrud Brauch,Michael Bremer,Ignacio Briceño,Thomas Brüning,Barbara Burwinkel,David Cameron,Nicola J. Camp,Archie Campbell,Ãngel Carracedo,Jose E. Castelao,Melissa H. Cessna,Stephen J. Chanock,Hans Christiansen,J. Margriet Collée,F. Ménégaux,Sten Cornelissen,Kamila Czene,Thilo Dörk,Arif B. Ekici,Christoph Engel,Mikael Eriksson,Peter A. Fasching,Jonine D. Figueroa,Daehee Kang,Asta Försti,Marike Gabrielson,Manuela Gago-Domínguez,V. Georgoulias,Fabián Gil,Graham G. Giles,Gord Glendon,E. Gómez,Grethe I.G. Alnæs,Pascal Guénel,Andreas Hadjisavvas,Lothar Häberle,Eric Hahnen,Per Hall,Ute Hamann,Elaine F. Harkness,Jaana M. Hartikainen,Mikael Hartman,Wei He,Bernadette A. M. Heemskerk‐Gerritsen,Peter Hillemanns,Sofia Khan,Antoinette Hollestelle,Weang-Kee Ho,Maartje J. Hooning,Anthony Howell,Keith Humphreys,Fauziah Mohamad Idris,Anna Jakubowska,Audrey Jung,Pooja Middha Kapoor,Michael J. Kerin,Э. К. Хуснутдинова,Zisun Kim,Yon‐Dschun Ko,Veli‐Matti Kosma,Vessela N. Kristensen,Kyriacos Kyriacou,Inge M.M. Lakeman,Jong Won Lee,Min Hyuk Lee,Jingmei Li,Annika Lindblom,Wing‐Yee Lo,Maria A. Loizidou,Artitaya Lophatananon,Jan Lubiński,Robert J. MacInnis,Michael J. Madsen,Anne‐Lise Børresen‐Dale,Miriam Dwek,Siranoush Manoukian,Annika Lindblom,Marı́a Elena Martı́nez,Tabea Maurer,Dimitrios Mavroudis,Catriona McLean,Mikael Eriksson,Arjen R. Mensenkamp,Kyriaki Michailidou,Austin Miller,Nur Aishah Mohd Taib,Kenneth Muir,Anna Marie Mulligan,Heli Nevanlinna,William G. Newman,Børge G. Nordestgaard,Pei-Sze Ng,Olivier Caron,Sue K. Park,Tjoung‐Won Park‐Simon,José Ignacio Arias Pérez,Paolo Peterlongo,David J. Porteous,Karolina Prajzendanc,Darya Prokofyeva,Paolo Radice,Kerstin Rhiem,Valerie Rhenius,Matti A. Rookus,Thomas Rüdiger,Emmanouil Saloustros,Elinor J. Sawyer,Arcangela De Nicolo,Andreas Schneeweiß,Peter Schürmann,Angela Cox,Christof Sohn,Melissa C. Southey,Harald Surowy,Maija Suvanto,Somchai Thanasitthichai,Ian Tomlinson,Diana Torres,Thérèse Truong,Maria Tzardi,Я В Валова,Christi J. van Asperen,Rob M. van Dam,Arjen R. Mensenkamp,Lizet E. van der Kolk,Elke M. van Veen,Camilla Wendt,Justin A. Williams,Xiaohong R. Yang,Sook‐Yee Yoon,M. Pilar Zamora,D. Gareth Evans,Geertruida H. de Bock,Jacques Simard,Antonis C. Antoniou,Kathleen Claes,Irene L. Andrulis,Jenny Chang‐Claude,Montserrat García‐Closas,Georgia Chenevix‐Trench,Roger L. Milne,Paul D.P. Pharoah,Marjanka K. Schmidt,Amanda B. Spurdle,Maaike P.G. Vreeswijk,Javier Benı́tez,Alison M. Dunning,Anders Kvist,Soo‐Hwang Teo,Peter Devilee,Douglas F. Easton

出处

期刊：The New England Journal of Medicine [New England Journal of Medicine]
日期：2021-01-20 卷期号：384 (5): 428-439 被引量：695

链接

nejm.org eur.nl rug.nl ru.nl handle.net ru.nl rug.nl rug.nl ac.uk ac.uk ac.uk handle.net universiteitleiden.nl ac.uk ac.uk nih.gov nih.govdoi.org

标识

DOI：10.1056/nejmoa1913948

摘要

Genetic testing for breast cancer susceptibility is widely used, but for many genes, evidence of an association with breast cancer is weak, underlying risk estimates are imprecise, and reliable subtype-specific risk estimates are lacking.

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Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women

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