Polarity reversal and invasion, metastasis of invasive micropapillary carcinoma

Invasive micropapillary carcinoma is a kind of malignant tumor with high risk of invasion and metastasis, which can occur to the breast, lung, bladder and other organs. Because of its high degree of lymphatic invasion, lymph node metastasis and the special histological characteristics of polarity reversal, invasive micropapillary carcinoma (IMPC) gradually attracted the attention of domestic and foreign pathologists and clinicians. In this paper, we reviewed the relationship between the histological features of IMPC and its high risk of invasion and metastasis from the polarity reversal point. Key words: Invasive micropapillary carcinoma; Polarity; Invasive; Metastasis