Traditional and Novel Methods for Cocrystal Formation: A Mini Review

Pharmaceutical cocrystal is one of solid-state modification for drug sub-stance, mainly for solubility improvement. Traditionally, cocrystal can be prepared by solvent evaporation method, grinding, and slurry method, but, every method has limitation for certain condition. The current trend for cocrystal formation uses the sophisticated method such as hot-melt extru-sion method, spray drying method, supercritical fluid technology and the newest, and laser irradiation method. Development of new method is not only to overcome the limitation of traditional cocrystallization methods but also to generate a simpler step and continuous process for the production of cocrystal product. This article gives a brief explanation of each method that can be used to generate pharmaceutical cocrystals.   How to Cite this Article Pubmed Style Kuni Zu'aimah Barikah. and Novel Methods for Cocrystal Formation: A Mini Review. SRP. 2018; 9(1): 79-82. doi:10.5530/srp.2018.1.15 Web Style Kuni Zu'aimah Barikah. and Novel Methods for Cocrystal Formation: A Mini Review. http://www.sysrevpharm.org/?mno=302644553 [Access: March 28, 2021]. doi:10.5530/srp.2018.1.15 AMA (American Medical Association) Style Kuni Zu'aimah Barikah. and Novel Methods for Cocrystal Formation: A Mini Review. SRP. 2018; 9(1): 79-82. doi:10.5530/srp.2018.1.15 Vancouver/ICMJE Style Kuni Zu'aimah Barikah. and Novel Methods for Cocrystal Formation: A Mini Review. SRP. (2018), [cited March 28, 2021]; 9(1): 79-82. doi:10.5530/srp.2018.1.15 Harvard Style Kuni Zu'aimah Barikah (2018) and Novel Methods for Cocrystal Formation: A Mini Review. SRP, 9 (1), 79-82. doi:10.5530/srp.2018.1.15 Turabian Style Kuni Zu'aimah Barikah. 2018. and Novel Methods for Cocrystal Formation: A Mini Reviews in Pharmacy, 9 (1), 79-82. doi:10.5530/srp.2018.1.15 Chicago Style Kuni Zu'aimah Barikah. Traditional and Novel Methods for Cocrystal Formation: A Mini Review. Systematic Reviews in Pharmacy 9 (2018), 79-82. doi:10.5530/srp.2018.1.15 MLA (The Modern Language Association) Style Kuni Zu'aimah Barikah. Traditional and Novel Methods for Cocrystal Formation: A Mini Review. Systematic Reviews in Pharmacy 9.1 (2018), 79-82. Print. doi:10.5530/srp.2018.1.15 APA (American Psychological Association) Style Kuni Zu'aimah Barikah (2018) and Novel Methods for Cocrystal Formation: A Mini Reviews in Pharmacy, 9 (1), 79-82. doi:10.5530/srp.2018.1.15