部分
分子内力
戒指(化学)
高分子化学
二羧酸
二胺
折叠(DSP实现)
环戊烷
氢键
化学
螺旋(腹足类)
材料科学
结晶学
立体化学
有机化学
分子
工程类
电气工程
生物
蜗牛
生态学
作者
Sunglim Choi,Ilia A. Guzei,Younghun Kim,Philjae Kang,Soo Hyuk Choi
标识
DOI:10.1002/cplu.202100239
摘要
A series of nylon-like oligomers was synthesized, which consisted of alternating cyclic 1,2-diamine and 1,2-dicarboxylic acid building blocks with a five-membered ring constraint. The nylon 2 4 oligomers are symmetric and display helical structures similar to the β-peptide 12-helix with intramolecular 12-membered ring hydrogen bonds. The cyclopentane moiety allows each building block to promote 12-helical folding. In addition, a tartaric acid derivative with the acetonide moiety increases the solubility of oligomers in common organic solvents and promotes helical folding.
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