The 5-year overall survival of cervical cancer in stage IIIC-r was little different to stage I and II: a retrospective analysis from a single center

医学 阶段(地层学) 宫颈癌 队列 磁共振成像 指南 淋巴 外科肿瘤学 放射科 回顾性队列研究 癌症 内科学 病理 生物 古生物学
作者
Ethan Yang,Shuying Huang,Xuting Ran,Yue Huang,Zhengyu Li
出处
期刊:BMC Cancer [Springer Nature]
卷期号:21 (1) 被引量:9
标识
DOI:10.1186/s12885-021-07890-w
摘要

Abstract Background The 2018 International Federation of Gynecology and Obstetrics (FIGO) staging guideline for cervical cancer includes stage IIIC recognized by preoperative radiology (IIIC-r) to state there are lymph nodes metastases (LNM) identified by imaging tools. We aim to explore the reasonability and limitations of stage IIIC-r and try to explore the potential reasons. Methods Electronic medical records were used to identify patients with cervical cancer. According to the new staging guidelines, patients were reclassified and assigned into five cohorts: stage I, stage II, stage IIIC-r, LNM confirmed by pathology (IIIC-p) and LNM detected by radiology and confirmed by pathology (IIIC r + p). Five-year overall survivals were estimated for each cohort. The diagnosis accuracy of computed tomography (CT), magnetic resonance imaging (MRI) and diameter of detected lymph nodes were also evaluated. Results A total of 619 patients were identified. The mean follow-up months were 65 months (95% CI 64.43–65.77) for all patients. By comparison, the 5-year overall survival rates were not statistically different ( p = 0.21) among stage IIIC-r, stage I and stage II. While, the rates were both statistical different ( p <0.001) among stage IIIC-p, IIIC r + p and stage I and stage II. The sensitivities of CT and MRI in detecting LNM preoperatively were 51.2 and 48.8%. The mean maximum diameter of pelvic lymph nodes detected by CT cohort was 1.2 cm in IIIC-r cohort, and was 1.3 cm in IIIC r + p cohort. While, the mean maximum diameter of pelvic lymph nodes detected by MRI was 1.2 cm in IIIC-r cohort, and was 1.48 cm in IIIC r + p cohort. When the diagnosis efficacy of the diameter of pelvic lymph nodes in detecting LNM were evaluated, the area under the receiver operating characteristic curve (ROC curve) was 0.58 ( p = 0.05). Conclusions It seems that the FIGO 2018 staging guideline for cervical cancer is likely to has certain limitations for the classification of those with LNM. CT or MRI, however, has limitations on detecting LNM. It would be better to use more accurate imaging tools to identify LNM in the clinical practices.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
3秒前
4秒前
loudly完成签到,获得积分10
4秒前
zqingqing完成签到,获得积分10
5秒前
阿呆在发呆关注了科研通微信公众号
6秒前
7秒前
8秒前
zhan发布了新的文献求助20
8秒前
咕噜完成签到,获得积分10
9秒前
10秒前
爆米花应助DONGLK采纳,获得10
10秒前
开朗以亦发布了新的文献求助10
11秒前
Zhang发布了新的文献求助10
11秒前
傲娇班发布了新的文献求助30
11秒前
12秒前
鄂成危发布了新的文献求助10
12秒前
袁翰将军完成签到 ,获得积分10
13秒前
whisper完成签到,获得积分10
13秒前
tachikoma应助JXY采纳,获得10
13秒前
digiwood完成签到,获得积分10
14秒前
15秒前
闵不悔完成签到,获得积分10
15秒前
robi发布了新的文献求助10
16秒前
龙龙不卷发布了新的文献求助10
16秒前
科研通AI2S应助xyz采纳,获得10
17秒前
小马甲应助云_123采纳,获得10
18秒前
18秒前
Zhang完成签到,获得积分10
19秒前
一二发布了新的文献求助10
20秒前
21秒前
搜集达人应助傻傻的磬采纳,获得10
22秒前
时尚大树完成签到,获得积分10
22秒前
顾念完成签到 ,获得积分10
22秒前
24秒前
木雷完成签到,获得积分20
24秒前
鄂成危完成签到,获得积分10
25秒前
26秒前
xuhongbo发布了新的文献求助10
27秒前
For完成签到,获得积分20
28秒前
Ava应助传统的如霜采纳,获得10
29秒前
高分求助中
Sustainability in Tides Chemistry 2800
The Young builders of New china : the visit of the delegation of the WFDY to the Chinese People's Republic 1000
Rechtsphilosophie 1000
Bayesian Models of Cognition:Reverse Engineering the Mind 888
Le dégorgement réflexe des Acridiens 800
Defense against predation 800
Very-high-order BVD Schemes Using β-variable THINC Method 568
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3134943
求助须知:如何正确求助?哪些是违规求助? 2785830
关于积分的说明 7774354
捐赠科研通 2441699
什么是DOI,文献DOI怎么找? 1298104
科研通“疑难数据库(出版商)”最低求助积分说明 625079
版权声明 600825