西力克角扁桃体
糖苷
化学
立体化学
乙酰胆碱酯酶
阿切
传统医学
生物化学
植物
生物
酶
医学
作者
Zhi-Tian Peng,Yingjie Xia,Takuya Yashiro,Xiong Gao,Tina Ting-Xia Dong,Karl Wah Keung Tsim,Huai‐You Wang
标识
DOI:10.1080/14786419.2022.2076230
摘要
Two new phenylpropanoids (1 and 2) and one new isoflavone glycoside (3), along with nine known compounds (4 − 12), were isolated from the pod of Ceratonia siliqua L. Their chemical structures were elucidated based on extensive spectroscopic analyses (1 D and 2 D NMR, UV, IR, and HRESIMS) and compared with the literature data. In addition, all isolated compounds were evaluated in vitro for inhibitory activity against acetylcholinesterase (AChE). Compounds 4, 5, and 12 showed inhibitory activity against acetylcholinesterase (AChE) with IC50 values ranging from 15.0 to 50.2 μM.
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