单核苷酸多态性
SNP公司
核苷酸多型性
生物
遗传学
遗传关联
基因组
全基因组关联研究
计算生物学
SNP阵列
人口
SNP基因分型
基因型
基因
医学
环境卫生
作者
Philipp E. Bayer,Mitchell Gill,Monica F. Danilevicz,David Edwards
出处
期刊:Methods in molecular biology
日期:2022-01-01
卷期号:: 153-159
被引量:2
标识
DOI:10.1007/978-1-0716-2237-7_9
摘要
Single-nucleotide polymorphisms (SNPs) have become the primary type of molecular genetic marker used in a diverse range of genetic and genomic studies. SNPs can be used to identify genomic regions linked to traits such as disease in genome-wide association studies, to understand population structure and diversity, or to understand mechanisms of genome evolution. One of the first steps of any SNP-based workflow, following SNP discovery, is quality control of SNP data. The protocol described here details how to perform quality control on SNP data to minimise errors in downstream analysis.
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