DPPH
食腐动物
自由基清除剂
姜科
化学
皮诺森布林
甲醇
有机化学
清除
抗氧化剂
色谱法
传统医学
根茎
类黄酮
医学
作者
Habsah Mohamad,Faridah Abas,Dharma Permana,Nordin H. Lajis,Abdul Manaf Ali,Mohd Aspollah Sukari,Taufiq Yap Yun Hin,Hiroe Kikuzaki,Nobuji Nakatani
标识
DOI:10.1515/znc-2004-11-1208
摘要
The methanol extract of the dried ripe fruits of Alpinia rafflesiana was investigated for its DPPH free radical scavenger constituents. 2′,3′,4′,6′-Tetrahydroxychalcone (7), which has never been isolated from natural sources was found to be most active as a DPPH free radical scavenger with the IC 50 value of 55 μᴍ. Other known compounds isolated from this species include 5,6-dehydrokawain (1), flavokawin B (2), 1,7-diphenyl-5-hydroxy-6-hepten-3-one (3), (-)-pinocembrin (4), cardamonin (5) and (-)-pinostrobin (6). The DPPH free radical scavenger compounds were detected using TLC autographic analysis. The percentage inhibition of DPPH free radical scavenging activity was measured on isolates (5-7) using colorimetric analysis.
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