水泡性口炎病毒
萌芽
生物
病毒学
小泡
病毒包膜
病毒
膜
衣壳
水泡性口炎
细胞生物学
遗传学
出处
期刊:Modern aspects of electrochemistry
日期:1976-01-01
卷期号:: 1-34
被引量:35
标识
DOI:10.1007/978-3-642-66306-2_1
摘要
Vesicular stomatitis virus (VS) is an enveloped Rhabdovirus which is capable of productively infecting a multitude of hosts including many mammalian species, fish, and insects (Howatson, 1970; Bussereau, 1973). Two serotypes of VS virus have been identified: VSIndiana and VSNew Jersey (Pringle, 1975). The standard infectious virions of either serotype are rods (rhabdos = rod) of approximately 175 × 68 nm which have one hemispherical and one planar end and contain a helical nucleocapsid of approximately 30 equal turns followed by 4 or 5 diminishing coils at the rounded end (Howatson, 1970) (Fig. 1). Thus, virions appear bullet-shaped. Numerous “spikes” measuring 10 nm in length project externally from the entire surface of the viral envelope. Defective interfering (DI) particles which have the same morphology but are shorter and contain incomplete genomes are also produced at high multiplicities of infection. The viral envelope is acquired during maturation when nucleocapsids bud through pre-existing cell membranes; the site of budding varies according to the host species and can be on either the plasma membrane or the membranes of intracytoplasmic vesicles or on both (Zee et al., 1970).
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