Quantitative trait loci mapping in an F2 Duroc × Pietrain resource population: I. Growth traits1

数量性状位点 特质 生物 资源(消歧) 人口 遗传学 人口学 计算机科学 基因 社会学 计算机网络 程序设计语言
作者
David B. Edwards,Catherine W. Ernst,Robert J. Tempelman,Guilherme J. M. Rosa,Nancy E. Raney,M. D. Hoge,R. O. Bates
出处
期刊:Journal of Animal Science [Oxford University Press]
卷期号:86 (2): 241-253 被引量:70
标识
DOI:10.2527/jas.2006-625
摘要

Pigs from the F(2) generation of a Duroc x Pietrain resource population were evaluated to discover QTL affecting growth and composition traits. Body weight and ultrasound estimates of 10th-rib backfat, last-rib backfat, and LM area were serially measured throughout development. Estimates of fat-free total lean, total body fat, empty body protein, empty body lipid, and ADG from 10 to 22 wk of age were calculated, and random regression analyses were performed to estimate individual animal phenotypes representing intercept and linear rates of increase in these serial traits. A total of 510 F(2) animals were genotyped for 124 micro-satellite markers evenly spaced across the genome. Data were analyzed with line cross, least squares regression, interval mapping methods using sex and litter as fixed effects. Significance thresholds of the F-statistic for single QTL with additive, dominance, or imprinted effects were determined at the chromosome- and genome-wise levels by permutation tests. A total of 43 QTL for 22 of the 29 measured traits were found to be significant at the 5% chromosome-wise level. Of these 43 QTL, 20 were significant at the 1% chromosome-wise significance threshold, 14 of these 20 were also significant at the 5% genome-wise significance threshold, and 10 of these 14 were also significant at the 1% genome-wise significance threshold. A total of 22 QTL for the animal random regression terms were found to be significant at the 5% chromosome-wise level. Of these 22 QTL, 6 were significant at the 1% chromosome-wise significance threshold, 4 of these 6 were also significant at the 5% genome-wise significance threshold, and 3 of these 4 were also significant at the 1% genome-wise significance threshold. Putative QTL were discovered for 10th-rib and last-rib backfat on SSC 6, body composition traits on SSC 9, backfat and lipid composition traits on SSC 11, 10th-rib backfat and total body fat tissue on SSC 12, and linear regression of last-rib backfat and total body fat tissue on SSC 8. These results will facilitate fine-mapping efforts to identify genes controlling growth and body composition of pigs that can be incorporated into marker-assisted selection programs to accelerate genetic improvement in pig populations.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
LaTeXer应助隐形夕阳采纳,获得50
刚刚
lw发布了新的文献求助10
1秒前
1秒前
英姑应助Janusfaces采纳,获得10
1秒前
1秒前
plasmid完成签到,获得积分10
2秒前
Ava应助咕噜咕噜咕嘟咕嘟采纳,获得10
2秒前
3秒前
SHAO应助一块司康饼采纳,获得100
3秒前
嗯哼发布了新的文献求助10
3秒前
Rondab应助mariawang采纳,获得10
5秒前
MchemG应助酷酷的紫南采纳,获得30
6秒前
1111发布了新的文献求助10
6秒前
6秒前
continue发布了新的文献求助10
7秒前
zhangtong发布了新的文献求助10
7秒前
嘟嘟完成签到,获得积分10
7秒前
wdy111应助葡萄味的果茶采纳,获得20
8秒前
悦耳代真完成签到,获得积分10
8秒前
ysx完成签到,获得积分10
8秒前
9秒前
Orange应助淡淡夕阳采纳,获得10
9秒前
9秒前
yar重新开启了yl文献应助
10秒前
11秒前
11秒前
zhoup完成签到,获得积分20
12秒前
宝海青完成签到,获得积分10
12秒前
李健应助缓慢的含双采纳,获得10
12秒前
yqb完成签到,获得积分10
13秒前
上官若男应助笑点低的不采纳,获得10
14秒前
量子星尘发布了新的文献求助10
15秒前
qifunongsuo1213完成签到,获得积分10
15秒前
chenzixin发布了新的文献求助10
15秒前
15秒前
明理致远发布了新的文献求助10
15秒前
yqb发布了新的文献求助10
15秒前
16秒前
alex完成签到,获得积分10
16秒前
研友_VZG7GZ应助受伤翠容采纳,获得10
16秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3988732
求助须知:如何正确求助?哪些是违规求助? 3531027
关于积分的说明 11252281
捐赠科研通 3269732
什么是DOI,文献DOI怎么找? 1804764
邀请新用户注册赠送积分活动 881869
科研通“疑难数据库(出版商)”最低求助积分说明 809021