作者
Emelia J. Benjamin,Kenneth Rice,Dan E. Arking,Arne Pfeufer,Charlotte van Noord,Albert V. Smith,Renate B. Schnabel,Joshua C. Bis,Eric Boerwinkle,Moritz F. Sinner,Abbas Dehghan,Steven A. Lubitz,Ralph B. D’Agostino,Thomas Lumley,Georg Ehret,Jan Heeringa,Thor Aspelund,Christopher Newton‐Cheh,Martin G. Larson,Kristin D. Marciante,Elsayed Z. Soliman,Fernando Rivadeneira,Thomas J. Wang,Guðný Eiríksdóttir,Daniel Levy,Bruce M. Psaty,Man Li,Alanna M. Chamberlain,Albert Hofman,Ramachandran S. Vasan,Tamara B. Harris,Jerome I. Rotter,W.H. Linda Kao,Sunil Agarwal,Bruno H. Stricker,Ke Wang,Lenore J. Launer,Nicholas L. Smith,Aravinda Chakravarti,André G. Uitterlinden,Philip A. Wolf,Nona Sotoodehnia,Anna Köttgen,Cornelia M. van Duijn,Thomas Meitinger,Martina Mueller,Siegfried Perz,Gerhard Steinbeck,H‐Erich Wichmann,Kathryn L. Lunetta,Susan R. Heckbert,Vilmundur Guðnason,Álvaro Alonso,Stefan Kääb,Patrick T. Ellinor,Jacqueline C.M. Witteman
摘要
We conducted meta-analyses of genome-wide association studies for atrial fibrillation (AF) in participants from five community-based cohorts. Meta-analyses of 896 prevalent (15,768 referents) and 2,517 incident (21,337 referents) AF cases identified a new locus for AF (ZFHX3, rs2106261, risk ratio RR = 1.19; P = 2.3 x 10(-7)). We replicated this association in an independent cohort from the German AF Network (odds ratio = 1.44; P = 1.6 x 10(-11); combined RR = 1.25; combined P = 1.8 x 10(-15)).
毛豆
Ganlou
lalala
良辰
丰知然
cocolu
mhl11
sissiarno
123
36456657
模糊中正
彭于彦祖
Billy
杳鸢
竹筏过海
shinysparrow
坚强的广山
tuanheqi
小柯
宜醉宜游宜睡
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