Asymmetric synthesis of chiral P-stereogenic triaryl phosphine oxides via Pd-catalyzed kinetic arylation of diaryl phosphine oxides

Enantioselective C–P cross-coupling of diarylphosphine oxides with ortho-substituted aryl iodides has been achieved via kinetic resolution strategy, affording chiral triarylphosphine oxides in high yields and with moderate to high enantioselectivity.