Kawan F. Kayani,Nian N. Mohammad,Dana A. Kader,Sewara J. Mohammed,Dana A. Shukur,Azad H. Alshatteri,Sabah H. Al‐Jaf,Karzan A. Abdalkarim,Hanar Q. Hassan
Abstract Developing a reliable portable biosensor is crucial for ensuring food safety and human health. This involves accurately detecting contaminants in food and water at their source. Smartphone cameras have recently become useful for capturing color or fluorescence changes that occur when a probe interacts with specific molecules on paper or in a chemical solution. Ratiometric designs, which self‐calibrate and minimize the impact of environmental changes, are gaining popularity. These designs rely on color changes or fluorescence shifts, which are easily assessable with smartphones. This overview highlights advances in ratiometric optical sensing using Metal‐organic frameworks (MOFs) with lanthanide components coupled with smartphones. These advancements allow contaminants in food and water to be visually identified. The article explains the principles, properties, and applications of color changes for visual detection in food safety. Using lanthanide metal‐organic frameworks with smartphones offers a potent method to detect contaminants, enhancing food safety and safeguarding human health.