Desmoplakin cardiomyopathy: a step towards understanding the genetic basis of phenotypic and outcome heterogeneity

Graphical AbstractThe diagnostic approach in a patient carrying a DSP P/LP variant. ARVC, arrhythmogenic right ventricular cardiomyopathy; CVD, cardiovascular disease; DCM, dilated cardiomyopathy; HF, heart failure; LGE, late gadolinium enhancement; LV, left ventricle; LVEF, left ventricular ejection fraction; LVED, left ventricular end diastole; LVES, left ventricular end systole; NDLVC, non-dilated left ventricular cardiomyopathy; NSVT, non-sustained ventricular tachycardia; PVCs, premature ventricular contractions; RV, right ventricle; RVEF, right ventricular ejection fraction; RVED, right ventricular end diastole; VA, ventricular arrhythmia.Open in new tabDownload slide