Seizure Outcome After Surgery for Refractory Epilepsy Diagnosed by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET/MRI): A Systematic Review and Meta-Analysis

医学 正电子发射断层摄影术 置信区间 癫痫 癫痫外科 磁共振成像 荟萃分析 优势比 氟脱氧葡萄糖 放射科 病变 耐火材料(行星科学) 颞叶 核医学 外科 内科学 精神科 物理 天体生物学
作者
Qingxia Kong,Xi-Bin Hu,Ling Yao,Shao-Min Lv,Jiahua Lv,Xinyu Wang,Mujie Guo,Kun Yu,Rui-Han Liu,Qingxia Kong
出处
期刊:World Neurosurgery [Elsevier]
卷期号:173: 34-43 被引量:1
标识
DOI:10.1016/j.wneu.2023.01.114
摘要

When magnetic resonance imaging (MRI) fails to detect an underlying epileptogenic lesion, the odds of a good outcome after epilepsy surgery are significantly lower (20%-65% compared with 60%-90% if a lesion is detected). We investigated the possible effects of introducing hybrid 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET)/MRI into the decision algorithm for patients with lesioned and nonlesioned drug-resistant epilepsy.Three databases were searched from January 1990 to October 2022. We registered the protocol with International Platform of Registered Systematic Review and Meta-analysis Protocols. Studies in which 18F-FDG PET/MRI was conducted with ≥12 months of postsurgical follow-up in patients with refractory epilepsy. Random-effects meta-analysis was used to calculate the proportion of patients with good outcomes. Metaregression was used to investigate sources of heterogeneity.We identified 8105 studies, of which 23 (1292 patients in total) were included. The overall good postoperative outcome rate was 71% (95% confidence interval 63.6-74.9). Good outcome was associated with the location of the refractory epileptic lesion (temporal lobe or extratemporal; risk ratio 1.27 [95% confidence interval 1.01-1.52], P = 0.009); Length of postoperative follow-up ≥40 months included in the same study accounted for 0.6% of the observed heterogeneity.Seventy-one percent of patients with refractory epilepsy and 18F-FDG PET/MRI epileptogenic lesion features had a good outcome of epilepsy after surgery. Our findings can be incorporated into routine preoperative consultations and emphasize the importance of the complete resection of the temporal lobe epileptogenic zone for 18F-FDG PET/MRI detection when safe and feasible.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
张wushudyej发布了新的文献求助10
2秒前
2秒前
小会发布了新的文献求助10
2秒前
努力学习发布了新的文献求助10
2秒前
子车茗应助科研通管家采纳,获得20
3秒前
小汪努力发SCI完成签到,获得积分10
3秒前
CHEN完成签到,获得积分10
3秒前
爱静静应助科研通管家采纳,获得10
3秒前
CodeCraft应助舒适的凡霜采纳,获得10
3秒前
共享精神应助秦磊采纳,获得10
3秒前
丘比特应助科研通管家采纳,获得10
3秒前
FashionBoy应助科研通管家采纳,获得30
3秒前
喜悦忆秋发布了新的文献求助10
3秒前
不配.应助科研通管家采纳,获得20
4秒前
CodeCraft应助科研通管家采纳,获得10
4秒前
JunMa应助科研通管家采纳,获得10
4秒前
ghost202完成签到,获得积分10
5秒前
5秒前
5秒前
贾济平发布了新的文献求助10
6秒前
金刚经应助汉桑波欸采纳,获得10
6秒前
Ivia完成签到,获得积分10
7秒前
7秒前
高高发布了新的文献求助10
8秒前
Leo完成签到,获得积分10
8秒前
8秒前
dan发布了新的文献求助10
10秒前
10秒前
调皮纸飞机完成签到,获得积分10
10秒前
song发布了新的文献求助10
10秒前
11秒前
11秒前
科研通AI2S应助人123456采纳,获得10
11秒前
lala完成签到,获得积分10
11秒前
ican完成签到,获得积分10
12秒前
芋圆完成签到,获得积分20
12秒前
chiyu完成签到,获得积分10
12秒前
香蕉觅云应助宝贝采纳,获得10
13秒前
Yang完成签到,获得积分10
13秒前
高分求助中
The late Devonian Standard Conodont Zonation 2000
Nickel superalloy market size, share, growth, trends, and forecast 2023-2030 2000
The Lali Section: An Excellent Reference Section for Upper - Devonian in South China 1500
Smart but Scattered: The Revolutionary Executive Skills Approach to Helping Kids Reach Their Potential (第二版) 1000
Very-high-order BVD Schemes Using β-variable THINC Method 850
Mantiden: Faszinierende Lauerjäger Faszinierende Lauerjäger 800
PraxisRatgeber: Mantiden: Faszinierende Lauerjäger 800
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3249612
求助须知:如何正确求助?哪些是违规求助? 2892819
关于积分的说明 8274355
捐赠科研通 2561099
什么是DOI,文献DOI怎么找? 1389559
科研通“疑难数据库(出版商)”最低求助积分说明 651256
邀请新用户注册赠送积分活动 627979