Randomized comparison of effect of standard antibiotic prophylaxis versus enhanced prophylactic measures on rate of urinary tract infection after flexible ureteroscopy

医学 预防性抗生素 泌尿系统 输尿管镜检查 无症状的 抗生素 随机对照试验 人口统计学的 B组 尿 外科 泌尿科 内科学 输尿管 人口学 社会学 微生物学 生物
作者
El-Sayed I. El-Agamy,Mohamed A. Elhelaly,Tamer A. Ali,Abdrabuh M. Abdrabuh,Mohamed F. Elebiary,Adel Elatreisy,Osama M. Ghoneimy,Basem A. Fathi,Mohamed Zamra,Khalid Kutub
出处
期刊:Archivio italiano di urologia, andrologia [PAGEPress Publications]
标识
DOI:10.4081/aiua.2023.11084
摘要

Purpose: To compare the rate of post-flexible ureteroscopy urinary tract infection (UTI) in patients subjected to the standard antibiotic prophylaxis alone versus enhanced prophylactic measures. Methods: A prospective randomized controlled study included 256 patients subjected to flexible ureteroscopy (FURS) for ureteral or renal stones from March 2018 to July 2022. Treatment groups included the standard antibiotic prophylaxis group (group 1, n=128) and the enhanced prophylaxis group (group 2, n=128). Patients in group 1 were injected with intravenous fluoroquinolone one hour preoperatively, and oral antibiotics were used for 24 h postoperatively. Patients in group 2 had urine culture ten days before the procedure; antibiotic-culture based was given for positive asymptomatic cases, while the procedure was deferred for active UTI. Results: The study groups were comparable regarding patient demographics, stone characteristics, operative time, and intraoperative complications. The overall hospitalization time was 1.68 ± 0.81 days. Postoperative, and overall complications were significantly higher in group 1 (15.6% vs. 6.3%, p = 0.04 and 26.6% vs. 17.2%, p = 0.047), respectively. Twenty patients (15.6 %) in the standard prophylaxis group were diagnosed with UTI in comparison to 8 patients (6.3 %) in the enhanced prophylaxis group (p = 0.047). Conclusions: Urinary tract infection after FURS could be reduced significantly by utilizing the suggested enhanced prophylactic approach.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
行隐完成签到,获得积分10
2秒前
2秒前
藜藜藜在乎你完成签到 ,获得积分10
4秒前
乐乐应助明亮无颜采纳,获得10
4秒前
顺利萧发布了新的文献求助10
4秒前
4秒前
6秒前
卷卷516发布了新的文献求助10
8秒前
小苏哥哥发布了新的文献求助10
10秒前
李健应助soda采纳,获得10
11秒前
14秒前
栗爷发布了新的文献求助30
14秒前
16秒前
18秒前
隐形曼青应助科研小趴菜采纳,获得10
19秒前
夭夭发布了新的文献求助10
19秒前
huangcx完成签到,获得积分10
19秒前
m彬m彬完成签到 ,获得积分10
21秒前
21秒前
xybjt发布了新的文献求助10
22秒前
24秒前
soda发布了新的文献求助10
26秒前
搜集达人应助科研通管家采纳,获得10
26秒前
小二郎应助科研通管家采纳,获得10
26秒前
彭于晏应助科研通管家采纳,获得10
26秒前
cdercder应助科研通管家采纳,获得30
26秒前
田様应助科研通管家采纳,获得10
26秒前
无花果应助科研通管家采纳,获得20
26秒前
chen应助科研通管家采纳,获得20
26秒前
快乐滑板应助科研通管家采纳,获得10
27秒前
cdercder应助科研通管家采纳,获得10
27秒前
劲秉应助科研通管家采纳,获得30
27秒前
今后应助听雨眠采纳,获得10
30秒前
天上人间发布了新的文献求助10
30秒前
顾矜应助卷卷516采纳,获得10
32秒前
cc应助淡定疾采纳,获得10
33秒前
34秒前
35秒前
35秒前
36秒前
高分求助中
Production Logging: Theoretical and Interpretive Elements 2500
Востребованный временем 2500
Aspects of Babylonian celestial divination : the lunar eclipse tablets of enuma anu enlil 1500
Agaricales of New Zealand 1: Pluteaceae - Entolomataceae 1040
Healthcare Finance: Modern Financial Analysis for Accelerating Biomedical Innovation 1000
Classics in Total Synthesis IV: New Targets, Strategies, Methods 1000
지식생태학: 생태학, 죽은 지식을 깨우다 600
热门求助领域 (近24小时)
化学 医学 材料科学 生物 工程类 有机化学 生物化学 纳米技术 内科学 物理 化学工程 计算机科学 复合材料 基因 遗传学 物理化学 催化作用 细胞生物学 免疫学 电极
热门帖子
关注 科研通微信公众号,转发送积分 3458771
求助须知:如何正确求助?哪些是违规求助? 3053518
关于积分的说明 9036928
捐赠科研通 2742726
什么是DOI,文献DOI怎么找? 1504524
科研通“疑难数据库(出版商)”最低求助积分说明 695319
邀请新用户注册赠送积分活动 694519