冷漠
无血性
萧条(经济学)
认知
精神科
心理学
神经影像学
临床心理学
认知障碍
痴呆
医学
疾病
内科学
精神分裂症(面向对象编程)
宏观经济学
经济
作者
D. S. Petelin,Sakeena Bairamova,O. Yu. Sorokina,Ilmar Nikolas V. Niinoja,А. Б. Локшина,B. A. Volel
标识
DOI:10.14412/2074-2711-2022-5-96-102
摘要
Depression is one of the most common mental disorders in neurological practice. Among other symptoms of depression, a symptom complex represented by apathy, anhedonia, and cognitive impairment plays an important role. This review presents the clinical characteristics of the symptoms described above and discusses modern neurochemical and neuroimaging concepts of their pathogenesis. The problem of pathogenetically substantiated therapy of depression with a predominance of apathy, anhedonia and cognitive impairment is discussed. Fundamental and clinical arguments are presented in favor of the high efficacy of vortioxetine in depression with a predominance of apathy, anhedonia, and cognitive impairment.
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