Transanal irrigation in children with functional constipation: A systematic review and meta‐analysis

医学 功能性便秘 荟萃分析 便秘 不利影响 排便 儿科 梅德林 物理疗法 外科 内科学 政治学 法学
作者
Rishi Bolia,Akhil Dhanesh Goel,Nikhil Thapar
出处
期刊:Journal of Pediatric Gastroenterology and Nutrition [Ovid Technologies (Wolters Kluwer)]
卷期号:78 (5): 1108-1115 被引量:1
标识
DOI:10.1002/jpn3.12200
摘要

Abstract Objectives Refractory functional constipation is a challenging condition to manage in children. The use of transanal irrigation (TAI) is well reported in children with neurological disorders as well as anorectal malformations but less so in children with functional disorders of defecation. The objective of our study was to evaluate the effectiveness, safety and outcomes of TAI in children with functional constipation. Methods PubMed, Scopus and Google Scholar were searched for publications related to the use of TAI in functional constipation. Data regarding the study design, sample size, patient characteristics, investigator‐reported response to TAI and adverse effects were extracted from studies that met the selection criteria. The inverse variance heterogeneity model was used for ascertaining the summary effect in this meta‐analysis. Results The search strategy yielded 279 articles of which five studies were included in the final review. The studies were from the United Kingdom ( n = 2), Netherlands ( n = 2) and Denmark ( n = 1). These studies included 192 children with a median age ranging from 7 to 12.2 years old. The TAI systems used in these studies were: Peristeen ( n = 2), Peristeen or Qufora ( n = 1), Alterna ( n = 1) and Navina ( n = 1). The follow‐up duration ranged from 5.5 months to 3 years. Eleven (5.7%) children did not tolerate TAI and withdrew from treatment soon after initiation. The pooled investigator‐reported success of TAI was 62% (95% CI: 52%–71%). The most common adverse event was pain which was experienced by 21.7% of children. A total of 27 (14%) were successfully weaned off TAI at the last follow‐up. Conclusions TAI is reported to be successful in 62% of children with refractory functional constipation. There is a need for well‐designed prospective trials to evaluate this treatment option in children with refractory functional constipation.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
崔雨旋完成签到,获得积分10
1秒前
mtj完成签到 ,获得积分10
1秒前
董璐发布了新的文献求助10
3秒前
李健的小迷弟应助xxx采纳,获得10
4秒前
科研通AI2S应助欢--采纳,获得10
7秒前
8秒前
8秒前
8秒前
dou完成签到,获得积分10
10秒前
蝉一个夏天完成签到,获得积分10
12秒前
天真的不尤完成签到 ,获得积分10
13秒前
14秒前
慕青应助龘龘龘采纳,获得10
15秒前
15秒前
yifan92完成签到,获得积分10
15秒前
16秒前
17秒前
汉堡包应助坦率的寻双采纳,获得10
17秒前
19秒前
笃定发布了新的文献求助10
20秒前
羞涩的萃发布了新的文献求助10
20秒前
21秒前
FancyShi发布了新的文献求助10
22秒前
dou发布了新的文献求助20
22秒前
24秒前
脑洞疼应助Ahha采纳,获得10
24秒前
25秒前
上官若男应助科研通管家采纳,获得10
25秒前
英姑应助科研通管家采纳,获得10
25秒前
小蘑菇应助科研通管家采纳,获得10
25秒前
SciGPT应助科研通管家采纳,获得10
25秒前
25秒前
lixiao应助科研通管家采纳,获得10
25秒前
打打应助科研通管家采纳,获得10
25秒前
脑洞疼应助科研通管家采纳,获得10
25秒前
wwz应助科研通管家采纳,获得10
25秒前
CipherSage应助科研通管家采纳,获得10
26秒前
搜集达人应助科研通管家采纳,获得10
26秒前
斯文败类应助科研通管家采纳,获得10
26秒前
Singularity应助科研通管家采纳,获得10
26秒前
高分求助中
Sustainability in Tides Chemistry 2800
Kinetics of the Esterification Between 2-[(4-hydroxybutoxy)carbonyl] Benzoic Acid with 1,4-Butanediol: Tetrabutyl Orthotitanate as Catalyst 1000
The Young builders of New china : the visit of the delegation of the WFDY to the Chinese People's Republic 1000
Rechtsphilosophie 1000
Bayesian Models of Cognition:Reverse Engineering the Mind 888
Handbook of Qualitative Cross-Cultural Research Methods 600
Very-high-order BVD Schemes Using β-variable THINC Method 568
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3137360
求助须知:如何正确求助?哪些是违规求助? 2788429
关于积分的说明 7786365
捐赠科研通 2444582
什么是DOI,文献DOI怎么找? 1300002
科研通“疑难数据库(出版商)”最低求助积分说明 625695
版权声明 601023