Aiming at the problems of large energy consumption, weak penetration and small coverage in the application of wide-area Internet of Things in home control system, a smart home control system based on ZigBee+NB-IoT heterogeneous networking technology is designed. With STM32 as the main control chip, the system uses sensors to collect temperature and humidity, light intensity, smoke concentration and other parameters, and uses ZigBee+NB-IoT technology to transmit the data to the client, so as to carry out intelligent control and management of home gateway. The test results show that the application of ZigBee+NB-IoT technology in smart home control system has the advantages of convenient networking, low power consumption, stable system connection and reliable operation, and has a good application prospect.