聚合酶
病毒
病毒学
呼吸系统
医学
生物
酶
内科学
生物化学
作者
Minh T. Tran,Sandrine Grosse,Rodrigo J. Carbajo,Edgar Jacoby,Yanting Yin,Xiaodi Yu,Carol Martinez,Bart Stoops,Ludwig Cooymans,Lili Hu,Ferdinand H. Lutter,Serge Pieters,Eric Tan,Jesús Alcázar,Dirk Roymans,Herman van Vlijmen,Peter Rigaux,Sujata Sharma,Tim H. M. Jonckers
标识
DOI:10.1021/acsmedchemlett.4c00272
摘要
Despite the availability of medicines preventing respiratory syncytial virus (RSV) infection, post-exposure treatment options are needed for addressing patient's needs. RSV non-nucleoside polymerase inhibitors (NNI) have emerged as a promising asset for which our group previously disclosed JNJ-8003 with potent
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