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Sulfonic Acid: Key Drug Design Elements With potent, broad-ranging Pharmacological Activities

钥匙(锁) 药物发现 药品 化学 医学 药理学 生物化学 计算机科学 计算机安全
作者
Lide Hu,Huinan Jia,Jiwei Zhang,Edeildo Ferreira da Silva‐Júnior,Chuanfeng Liu,Xinyong Liu,Peng Zhan
出处
期刊:Future Medicinal Chemistry [Newlands Press Ltd]
卷期号:15 (22): 2029-2032 被引量:4
标识
DOI:10.4155/fmc-2023-0257
摘要

Future Medicinal ChemistryVol. 15, No. 22 EditorialSulfonic acid: key drug design elements with potent, broad-ranging pharmacological activitiesLide Hu‡, Huinan Jia‡, Jiwei Zhang, Edeildo Ferreira da Silva-Júnior, Chuanfeng Liu, Xinyong Liu & Peng ZhanLide Hu‡Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, Shandong, 250012, PR China, Huinan Jia‡Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, Shandong, 250012, PR China, Jiwei ZhangDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, Shandong, 250012, PR China, Edeildo Ferreira da Silva-JúniorBiological & Molecular Chemistry Research Group, Institute of Chemistry & Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, AC, Simoes Campus, Alagoas, Macei, 57072-970, Brazil, Chuanfeng Liu*Author for correspondence: E-mail Address: liuchuanfeng214@163.comDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, Shandong, 250012, PR ChinaSuzhou Research Institute of Shandong University, Room 607, Building B of NUSP, NO. 388 Ruoshui Road, SIP, Suzhou, Jiangsu, 215123, PR China, Xinyong Liu**Author for correspondence: E-mail Address: xinyongl@sdu.edu.cnDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, Shandong, 250012, PR China & Peng Zhan ***Author for correspondence: E-mail Address: zhanpeng1982@sdu.edu.cnhttps://orcid.org/0009-0003-4356-4594Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, Shandong, 250012, PR ChinaPublished Online:6 Nov 2023https://doi.org/10.4155/fmc-2023-0257AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInRedditEmail View articleKeywords: drug designmedicinal chemistrysulfonic acidReferences1. 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Anti-inflammatory effects of naringenin 8-sulphonate from parinari excelsa sabine stem bark and its semi-synthetic derivatives. Bioorg. Chem. 138, doi: 10.1016/j.bioorg.2023.106614 (2023).Crossref, Medline, Google Scholar14. Matesanz M, Mensa J. Ceftazidime-avibactam. Rev. Esp. Quimioter. 34(Suppl. 1), 38–40 (2021).Crossref, Medline, Google Scholar15. Heo YA. Imipenem/cilastatin/relebactam: a review in Gram-negative bacterial infections. Drugs 81(3), 377–388 (2021).Crossref, Medline, CAS, Google Scholar16. Büscher P, Cecchi G, Jamonneau V, Priotto G. Human african trypanosomiasis. Lancet 390(10110), 2397–2409 (2017).Crossref, Medline, Google Scholar17. Hawking F. Chemotherapy of onchocerciasis. Transactions of the Royal Society of Tropical Medicine. Hygiene 52(2), 109–111 (1958).CAS, Google Scholar18. Yahi N, Sabatier JM, Nickel P, Mabrouk K, Gonzalez-Scarano F, Fantini J. Suramin inhibits binding of the V3 region of HIV-1 envelope glycoprotein gp120 to galactosylceramide, the receptor for HIV-1 gp120 on human colon epithelial cells. J. Biol. Chem. 269(39), 24349–24353 (1994).Crossref, Medline, CAS, Google Scholar19. Sahu D, Saroha A, Roy S, Das S, Srivastava PS, Das HR. Suramin ameliorates collagen induced arthritis. Int. Immunopharmacol. 12(1), 288–293 (2012).Crossref, Medline, CAS, Google Scholar20. Williams WL. The effects of suramin (germanin), azo dyes, and vasodilators on mice with transplanted lymphosarcomas. Cancer Res. 6, 344–353 (1946).Medline, CAS, Google ScholarFiguresReferencesRelatedDetails Vol. 15, No. 22 STAY CONNECTED Metrics Downloaded 25 times History Received 1 September 2023 Accepted 15 September 2023 Published online 6 November 2023 Published in print November 2023 Information© 2023 Newlands PressKeywordsdrug designmedicinal chemistrysulfonic acidAuthor contributionsThe writing of the first draft was initiated by C Liu, L Hu and H Jia. E Ferreira da Silva-Júnior, X Liu and P Zhan edited the manuscript. P Zhan reviewed and approved the final manuscript.Financial disclosureThe authors have received financial support from the National Natural Science Foundation of China (NSFC nos. 82173677, 82211530493), and the Science Foundation for Outstanding Young Scholars of Shandong Province (ZR2020JQ31). Natural Science Foundation of Jiangsu Province (SBK2023041680); China Postdoctoral Science Foundation (2022M711938). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.Competing interests disclosureThe authors have no competing interests or relevant affiliations with any organization or entity with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.Writing disclosureNo writing assistance was utilized in the production of this manuscript.PDF download
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