炎症
自愈水凝胶
弹性蛋白酶
化学
中性粒细胞弹性蛋白酶
酶
免疫学
医学
生物化学
高分子化学
作者
Tina Helmecke,Dominik Hahn,Nadine Matzke,Lisa A. Ferdinand,Lars Franke,Sebastian Kühn,Gunter Fischer,Carsten Werner,Manfred F. Maitz
标识
DOI:10.1002/advs.202370037
摘要
Inflammation-Controlled Anti-Inflammatory Hydrogels In article number 2206412, Carsten Werner, Manfred F. Maitz, and co-workers designed an enzymatically cleavable polymer hydrogel platform for the release of anti-inflammatory molecules in response to the inflammation status of human blood. Inflammation suppression reduces the release of the trigger enzyme elastase from activated granulocytes and down-regulates hydrogel cleavage.
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