DNA损伤
DNA修复
保护
计算生物学
生物
DNA
生物信息学
计算机科学
遗传学
医学
护理部
作者
Jiawei Chen,Ravi Potlapalli,Heng Quan,Lingtao Chen,Ying Xie,Seyedamin Pouriyeh,Nazmus Sakib,Lichao Liu,Yixin Xie
出处
期刊:Biotech
[Multidisciplinary Digital Publishing Institute]
日期:2024-01-16
卷期号:13 (1): 3-3
被引量:5
标识
DOI:10.3390/biotech13010003
摘要
DNA damage is a critical factor contributing to genetic alterations, directly affecting human health, including developing diseases such as cancer and age-related disorders. DNA repair mechanisms play a pivotal role in safeguarding genetic integrity and preventing the onset of these ailments. Over the past decade, substantial progress and pivotal discoveries have been achieved in DNA damage and repair. This comprehensive review paper consolidates research efforts, focusing on DNA repair mechanisms, computational research methods, and associated databases. Our work is a valuable resource for scientists and researchers engaged in computational DNA research, offering the latest insights into DNA-related proteins, diseases, and cutting-edge methodologies. The review addresses key questions, including the major types of DNA damage, common DNA repair mechanisms, the availability of reliable databases for DNA damage and associated diseases, and the predominant computational research methods for enzymes involved in DNA damage and repair.
科研通智能强力驱动
Strongly Powered by AbleSci AI