Functionalized multiwall carbon nanotube-molybdenum disulphide nanocomposite based electrochemical ultrasensitive detection of neurotransmitter epinephrine

Epinephrine hormone as neurotransmitter is a crucial component for the efficient working of the human cardio-respiratory and central nervous or peripheral nervous systems. Efficient quantification of the epinephrine level in biological fluids is critical in diagnosing several significant diseases. The present research problem focused on the synthesized the multiwall carbon nanotubes (MW-CNTs) functionalized with MoS2 heterostructure using the hydrothermal route and further explored its applicability to detect neurotransmitter i.e. epinephrine. The morphological and structural characterization of the MoS2-MW/CNTs heterostructure was examined by employing morphological as well as spectroscopic techniques. Results showed that heterostructures were well decorated with 2-dimensional MoS2 nano-flakes, which enhance material electro-catalytic activity for better electrochemical communication. The results exhibit that the developed epinephrine biosensor exhibited a Limit of detection (LOD) of 3.0 μM, with good linearity from 9.9 to 137.9 μM, excellent selectivity and enhanced sensitivity with reproducibility. The proposed MoS2/MW-CNTs modified GCE electrode was stable in terms of performance and could be used for epinephrine sensing in the real water sample.