医学
原发性胆汁性肝硬化
流行病学
入射(几何)
内科学
原发性硬化性胆管炎
肝病
慢性肝病
疾病
生活质量(医疗保健)
肝硬化
胃肠病学
光学
物理
护理部
作者
Francesca Colapietro,Arianna Bertazzoni,Ana Lleò
标识
DOI:10.1016/j.cld.2022.06.001
摘要
Primary biliary cholangitis (PBC) is a cholestatic liver disease with potential evolution to liver cirrhosis when left untreated. Despite being rare, PBC has a substantial impact on the quality of life and survival of affected patients. Women are the most diagnosed worldwide; however, male subjects seem to have more aggressive disease and worse prognosis. Changing epidemiologic trends are emerging in PBC, with increasing global prevalence and slight smoothing of sex differences. In this review we present available data on incidence rates and prevalence of PBC worldwide, highlighting geographic differences and factors impacting clinical outcomes.
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