医学
心肌炎
发病机制
病毒
重症监护医学
并发症
心力衰竭
动脉
冠状动脉疾病
免疫学
心脏病学
生物信息学
内科学
生物
作者
Xinying Chen,Yingying Li,Lijun Deng,Lili Wang,Wenting Zhong,Junbin Hong,Liyu Chen,Jing-Hua Yang,Bin Huang,Xiaolan Xiao
标识
DOI:10.3389/fimmu.2023.1188330
摘要
Cardiovascular involvement is an uncommon but severe complication of Epstein–Barr virus (EBV) infection caused by direct damage and immune injury. Recently, it has drawn increasing attention due to its dismal prognosis. It can manifest in various ways, including coronary artery dilation (CAD), coronary artery aneurysm (CAA), myocarditis, arrhythmias, and heart failure, among others. If not treated promptly, cardiovascular damage can progress over time and even lead to death, which poses a challenge to clinicians. Early diagnosis and treatment can improve the prognosis and reduce mortality. However, there is a lack of reliable large-scale data and evidence-based guidance for the management of cardiovascular damage. Consequently, in this review, we attempt to synthesize the present knowledge of cardiovascular damage associated with EBV and to provide an overview of the pathogenesis, classification, treatment, and prognosis, which may enhance the recognition of cardiovascular complications related to EBV and may be valuable to their clinical management.
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