曲妥珠单抗
转移性乳腺癌
乳腺癌
肿瘤科
医学
内分泌系统
内科学
癌症
激素
作者
Aditya Bardia,Xichun Hu,Rebecca Dent,Kan Yonemori,Carlos H. Barrios,Joyce O’Shaughnessy,Hans Wildiers,Jean‐Yves Pierga,Qingyuan Zhang,Cristina Saura,Laura Biganzoli,Joohyuk Sohn,Seock‐Ah Im,Christelle Lévy,William Jacot,Natasha Begbie,Jun Ke,Gargi Patel,Giuseppe Curigliano
标识
DOI：10.1056/nejmoa2407086
摘要
Outcomes in patients with hormone receptor-positive metastatic breast cancer worsen after one or more lines of endocrine-based therapy. Trastuzumab deruxtecan has shown efficacy in patients with metastatic breast cancer with low expression of human epidermal growth factor receptor 2 (HER2) after previous chemotherapy.
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