蛋白质功能
计算机科学
蛋白质功能预测
功能(生物学)
计算生物学
蛋白质结构预测
生物信息学
生物
蛋白质结构
进化生物学
遗传学
生物化学
基因
作者
Xinyuan He,Yang Liu,Xianghe Zeng,Rongfeng Gao,Zhen Tian,Xiangyu Fan
出处
期刊:PubMed
日期:2024-07-25
卷期号:40 (7): 2087-2099
标识
DOI:10.13345/j.cjb.230675
摘要
With the increasing of computer power and rapid expansion of biological data, the application of bioinformatics tools has become the mainstream approach to address biological problems. The accurate identification of protein function by bioinformatics tools is crucial for both biomedical research and drug discovery, making it a hot topic of research. In this paper, we categorize bioinformatics-based protein function prediction methods into three categories: protein sequence-based methods, protein structure-based methods, and protein interaction networks-based methods. We further analyze these specific algorithms, highlighting the latest research advancements and providing valuable references for the application of bioinformatics-based protein function prediction in biomedical research and drug discovery.
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