Wnt信号通路
PI3K/AKT/mTOR通路
转移
长非编码RNA
肿瘤进展
信号转导
癌症研究
癌症
生物
生物信息学
核糖核酸
计算生物学
医学
基因
遗传学
作者
Qiang Yi,Gangfeng Zhu,Weijian Zhu,Sheng Wang,Xinting Ouyang,Kuan Yang,Yu Fan,Jinghua Zhong
出处
期刊:Heliyon
[Elsevier]
日期:2024-09-01
卷期号:10 (18): e37527-e37527
标识
DOI:10.1016/j.heliyon.2024.e37527
摘要
LINC01094 is a long non-coding RNA that plays a crucial role in cancer progression by modulating key signaling pathways, such as PI3K/AKT, Wnt/β-catenin and TGF-β Signaling Pathway Feedback Loop. In this review we summarize the recent research on the functional mechanisms of LINC01094 in various cancers, including its impact on tumor growth, metastasis, and resistance to therapy. We also discuss the therapeutic potential of targeting LINC01094 and highlight the current strategies and challenges in this area. Perspectives on future development of LINC01094-based therapies are also provided.
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