作者
Eric M. Kofoed,Ignacio Aliagas,Terry D. Crawford,Jialin Mao,Seth F. Harris,Min Xu,Shumei Wang,Ping Wu,Fang Ma,Kevin Clark,Jessica Sims,Yiming Xu,Yutian Peng,Elizabeth Skippington,Jing Wang,Janina Reeder,Savita Ubhayakar,Matt Baumgardner,Zhengyin Yan,Jacob Chen,Summer Park,Hua Zhang,Chun‐Wan Yen,María Lorenzo,Nicholas J. Skelton,Xiaorong Liang,Liuxi Chen,Bridget Hoag,Chun Sing Li,Zhiguo Liu,John Wai,Xingrong Liu,Jun Liang,Man‐Wah Tan
摘要
Guanine nucleotides are required for growth and viability of cells due to their structural role in DNA and RNA, and their regulatory roles in translation, signal transduction, and cell division. The natural antibiotic mycophenolic acid (MPA) targets the rate-limiting step in